Scientists have developed a mouthwash
that allows plaque-causing bacteria to be destroyed
using nothing more than a bright light.
It works using the same principles as some skin cancer
treatments.
Leeds Dental Institute say it may be available inside
three years for home use - perhaps with the light
attached to the head of a toothbrush.
The same team is also working on a "repair solution"
to help the body grow new enamel.
They believe this could reduce the need for "drilling
and filling".
Both projects are being spearheaded by Professor Jennifer
Kirkham, who believes they could make a big difference
to dental care.
The mouthwash uses "photodynamic therapy",
and Professor Kirkham sees it as a way to help people
who find it hard to use a toothbrush.
Antibacterial molecules in the liquid are absorbed
only by plaque-causing bacteria, and activated when
a bright light is shone into the mouth, killing them.
Cancer application
The same technique is used in certain types of skin
cancer, with the substance painted on the target area,
taken up by cancer cells, then exposed to light of
a certain wavelength, which activates it to kill the
cancer cell.
Although the molecule is known to be safe for human
consumption, full trials have yet to be completed.
Prof Kirkham said: "The laboratory is looking
to find safe new ways to control plaque which do not
rely on toothpaste.
"We see patients in the clinic who are not able
to brush effectively - the shape of the mouth may
not allow sufficient access, the patient could be
disabled or just not a proficient brusher."
Machines offering photodynamic therapy in dental
clinics already exist, but another researcher, Dr
Simon Wood, said that the aim was to find a way the
mouthwash could be used at home.
He said: "In our experiments, we've been using
standard white light - I've been using a conventional
security light.
"While you'd need a bright light to make it
work, you could in theory have something in the head
of a toothbrush."
Self-repair
The "repair solution" is made from a protein
which encourages the laying down of new enamel over
microscopic holes in teeth, including those caused
by acid produced by plaque bacteria.
The liquid is painted on, enters the holes, then
attracts the calcium needed to patch them.
Prof Kirkham said it could help people with early damage
which could eventually lead to dental decay, or who
have tiny holes in their teeth which make consuming
hot or cold food or drink painful.
The repair solution will not eliminate the need for
the dentist's drill - bigger cavities filled with
decay would still have to be treated in the conventional
way.
It is hoped that it will enter trials next year,
and gain a licence for wider use within five years.