ALERT Canadians: Toxic Ingredients
in the Arepanrix H1N1 Vaccine Harm Your Health
Health Canada has authorized the sale of Arepanrix™
H1N1 vaccine based on no conclusive clinical testing. The
authorization is based on the Health Canada review of available
data on the quality, safety and immunogenicity of similar vaccines,
which established the benefit/risk profile in favour of inoculating
the Canadian population.
Read the Notice
of Decision issued by Health Canada. The decision by the Health
Minister was based on a belief (not qualified or informed) that
immediate action is required to deal with the H1N1 risk. The assertion
that the decision is based on limited clinical testing is being
misapplied. There has been NO conclusive results from any clinical
trials on the Arepanrix H1N1 vaccine.
This report is designed to inform you how the risks outweigh the
benefits of the vaccine. It will demonstrate how the Health Canada
assessment is flawed and contradictory to established research
on the detrimental health effects of the vaccine ingredients contained
in Arepanrix.
Arepanrix™ H1N1 (AS03-adjuvanted H1N1 pandemic influenza
vaccine) is a two-component vaccine consisting of an H1N1 antigen
(as a suspension), and an AS03 adjuvant (as an oil-in-water emulsion).
The virus is inactivated followed by formaldehyde treatment and
disrupted with sodium deoxycholate.
Preservative content:
5µg (micrograms) Thimerosal USP per 0.5mL dose or 2.5 micrograms
organic mercury (Hg) per 0.5mL dose
Adjuvant:
The AS03 adjuvant system is composed of DL-α-tocopherol,
squalene and polysorbate 80 in a 3mL vial:
According to the Australian National Research Council, fewer than
20% but perhaps more than 10% of the general population may be
susceptible to formaldehyde and may react acutely at any exposure
level.
More hazardous than most chemicals in 5 out of 12 ranking systems,
on at least 8 federal regulatory lists, it is ranked as one of
the most hazardous compounds (worst 10%) to ecosystems and human
health (Environmental Defense Fund).
Formalyn a 37 percent solution of gaseous formaldehyde which includes
methano (used in vaccines as a tissue fixative) is considered
a hazardous compound, and its vapor is toxic.
In the body, formaldehyde can cause proteins to irreversibly bind
to DNA. Laboratory animals exposed to doses of inhaled formaldehyde
over their lifetimes have developed more cancers of the nose and
throat than are usual, as have workers in particle-board sawmills…
Formaldehyde is classifed as a probable human carcinogen by the
U.S. Environmental Protection Agency and as a known human carcinogen
by the International Agency for Research on Cancer. Sodium Deoxycholate
Sodium Deoxycholate is a water soluble ionic detergent/bile
salt which causes cell death and symptoms such as burning, redness,
and swelling. It has been shown to weaken the blood-brain-barrier
(BBB) and subsequently activate seizures. It has demonstrated
synergistic toxicity with antifungal drugs.
Detergents and emulsifiers promote tumors and cause cells to
leak or explode by weakening their walls, with no mechanism for
regulating destructive activity. These chemicals are not completely
purified out of the final vaccine product, so they enter the body
at the time of injection.
Detergents are used extensively in cell research precisely because
of their ability to break cells open for further analysis. This
catastrophically mimics the membrane attack complex (MAC). Detergents
hit cells at random and continue destroying cells regardless of
which call off the attack.
Sodium Deoxycholate is completely foreign to the relationships
that define and make up the delicate balance of the immune system.
It systematically disrupts these relationships to negate the optimal
function and design of immune responses.
Thimerosal has powerful and damaging effects on cells of the nervous
and immune systems in mammals including humans. Its effect may
vary depending on the dose, the genetics of the individual, and
the timing of exposure. The mercury dose from thimerosal produces
acute and often deadly ethylmercury blood levels.
Organic forms of mercury are well-known neurotoxic agents
and far more dangerous than inorganic mercury sources. Exposure
to organic mercury produces predominantly central nervous system
(CNS) effects that are commonly severe and can induce prolonged
unconsciousness, coma and death. (See: Acta
Chim. Slov. 2004, 51, 361-372) After only 2 hour exposures, thimerosal at micromolar concentrations
causes neuronal membrane damage and alterations leading to cell
death in immune T-cells.
Thimerosal alters the functioning of critical neurotransmitters
necessary for proper brain functioning. Thimerosal causes DNA fragmentation of neuronal cells and
disrupts
neuronal growth factor signaling at micromolar and even nanomolar
concentrations. It also causes DNA methylation and attentional
pathways at nanomolar concentrations, leading to alterations in
brain function.
Under microscopic
magnification the following video presentation by the University
of Calgary demonstrates the immediate damage mercury does to the
structure of brain cells.
Too dangerous for human use, Squalene is not officially licensed
for use in the United States or Canada. Oil adjuvants like squalene
have been ordinarily used to inflict diseases in animals –
for experimentation and study. According to anthrax vaccine expert
Gary Matsumoto and other reliable sources, the US military used
an unlicensed, experimental anthrax vaccination laced with squalene,
with disastrous consequences, including Gulf War Sydrome.
"There are now data in more than two dozen peer-reviewed
scientific papers, from ten different laboratories in the US,
Europe, Asia and Australia, documenting that squalene-based adjuvants
can induce autoimmune diseases in animals, observed in mice, rats,
guinea pigs and rabbits. Sweden's Karolinska Institute has demonstrated
that squalene alone can induce the animal version of rheumatoid
arthritis. The Polish Academy of Sciences has shown that in animals,
squalene alone can produce catastrophic injury to the nervous
system and the brain. The University of Florida Medical School
has shown that in animals, squalene alone can induce production
of antibodies specifically associated with systemic lupus erythematosus"
writes Matsumoto.
Oil-based vaccination adjuvants like squalene have been proved
to generate concentrated, unremitting immune responses over long
periods of time according to a 2000 article in The American Journal
of Pathology. The study demonstrated that a single injection of
the adjuvant squalene into rats triggered a chronic, immune-mediated
joint-specific inflammation, also known as rheumatoid arthritis.
The researchers concluded the study raised questions about the
role of adjuvants in chronic inflammatory diseases.
Polysorbate 80 is similar to Sodium Deoxycholate in its ability
to increase cell permeability, damage, and bursting. After injection
it can rapidly metabolize into sorbitol and ethylene oxide which
is much more toxic than the original chemical. When Polysorbate
80 breaks down there are 20 moles of ethylene oxide for every
mole of sorbitol. These polysorbates have been shown to cause
dangerous, sometimes fatal effects, when given through a needle.
Changes in heart function can occur immediately. The blood-brain-barrier
(BBB) can be weakened and penetrated, followed by seizures and
even death. Polysorbates demonstrate synergistic toxicity with
a wide range of chemicals.
Polysorbate 80 has been found to negatively affect the immune
system and cause severe anaphylactic shock which can kill. According
to Annals of Allergy, Asthma and Immunology, Volume 95, Number
6, December 2005 , pp. 593-599(7), "it is of current relevance
as a 'hidden' inductor of anaphylactoid reactions", and "Polysorbate
80 was identified as the causative agent for the anaphylactoid
reaction of nonimmunologic origin in the patient. The study included
a pregnant woman who suffered anaphylactic shock after being given
a IV drip of multi-vitamins containing polysorbate 80.
In addition to this, there have been studies in Food and Chemical
Toxicology which showed that Polysorbate 80 causes infertility.
Baby female rats were injected with polysorbate 80 at days 4-7
after birth. It accelerated the maturing of the rats and caused
changes to the vagina and womb lining, hormonal changes, ovary
deformities and degenerative follicles.
According to the World Intellectual Property Organization, which
is part of the United Nations, scientists from the organization
are developing vaccines specifically to damage fertility as a
method of contraception. A suggested ingredient for the vaccine
is Polysorbate 80 (also known as tween 80). As it is a preferred
ingredient, scientists are obviously aware of its ability to cause
infertility.
There are currently NO clinical trials or results which have validated
the long-term safety and efficacy of the Arepanrix H1N1vaccine
and its integrated AS03 adjuvant. Regulatory health agencies are
refusing to acknowledge this fact or the nature of toxicity levels
associated with Arepanrix and its ingredients. The well documented
toxicity evidence for each ingredient presented above is simply
being ignored.
A simple search on the ClinicalTrials.gov
website shows that three "Rapid Evaluation" studies
for Arepanrix H1N1vaccine have not even initiated recruiting as
of the date this article was published.
One of the most critical elements which defines the toxicity potential
of any vaccine are its pharmacokinetic properties. GlaxoSmithKline
(GSK) and Health Canada do not consider the study, analysis
or evaluatation of the pharmacokinetic
properties of any vaccine including Arepanrix. This means
that the bodily absorption, distribution, metabolism and excretion
of ingredients within the Arepanrix vaccine are not known or even
considered in safety assessments. This in itself is a highly suspicious
and negligent behavior which leaves many questions on the credbility
and reputability of GlaxoSmithKline and Health Canada and their
motives for marketing this vaccine to the Canadian population.
Adults aged 18-60 years: Dosage recommendations of 0.5ml are based on very limited
clinical evidence of safety and immunogenicity data available
from two 3-week studies.Neither study has validated the
long-term immunogencity, safety, toxicity, or pharmacodynamics
of the vaccine based on any dosage.Clinically, the shortest
acceptable period to study the side effects of any vaccine is
6-8 weeks. The accepted studies noted by GSK and Health Canada
are half this period.
Elderly (>60 years):
No clinical data are available for Arepanrix H1N1 in this age
group including the effects of the AS03 squalene adjuvant. There
is no data to justify any safe dosage in this age group.
Children and Adolescents aged 10-17 years:
No clinical data are available for Arepanrix H1N1 in this age
group including the effects of the AS03 squalene adjuvant. No
exact dosing recommendations can be made.
Children aged from 6-35 months:
No clinical data are available for Arepanrix H1N1 in this age
group including the effects of the AS03 squalene adjuvant. No
exact dosing recommendations can be made.
Pregnancy and Lactation No data have been generated in pregnant or breast feeding
women with Arepanrix nor with the AS03 adjuvant.
Fertility & Sterility
GSK suggests animal studies have not demonstrated harmful effects
with respect to fertility which directly contradicts several scientific
studies which show that Polysorbate
80 causes infertility.
Interactions With Seasonal Flu Vaccines GSK claims that no data is available on the concomitant administration
of Arepanrix H1N1 with other vaccines, including seasonal influenza
vaccines.
Adverse reactions may be intensified with co-administration with
other vaccines.
Despite the suggested evidence in unpublished studies that seasonal
flu vaccines can increase the risk of H1N1 flu, Canadian provinces
are recommending co-administration of both vaccines in as little
as 60 days. This highly irresponsible recommedation by public
health officials could potentially devastate the health of millions
of Canadians. An example of the schedule of shots in Ontario is
listed in the chart below released in a leaflet to all Ontarians
in early October 2009.
Timing
Vaccination
Targeted Individuals
October 2009
Seasonal Flu
Ontarians 65 and over
November 2009
H1N1 Flu
All Ontarians
Dec/09 - Jan/10
Seasonal Flu
Ontarians under 65
The people in Ontario need to call the ServiceOntario INFOline
at
1-800-476-9708 and request information as to why Ontario is contradicting
studies which demonstrate the risks of administering both the
seasonal flu and H1N1 vaccine within short periods.
In addition, the Government of Ontario (and Canada) need to
respond to direct queries from the public to justify why and how
recommendations are being be made to administer the H1N1 vaccine
to those receiving the seasonal flu vaccine, when the studies
that test the safety and efficacy for the "Rapid
Evaluation of Pandemic H1N1 Influenza Vaccine in Adults Receiving
Seasonal Influenza Vaccine" have not yet started as of
late October 2009 (with no participants even being recruited).
Adverse Reactions Solicited adverse reactions were reported more frequently
in the H1N1+AS03 group compared to the H1N1 group based on 2 studies
which evaluated the safety of another AS03-adjuvanted vaccine
containing HA derived from A/California/7/2009 (H1N1)v-like (Pandemrix)
in healthy subjects aged 18-60 years.
Since 48.6 of the 50.4 million doses of Arepanrix ordered by the
Canadian government contain the AS03 adjuvant, we will focus on
those adverse reactions documented which are as follows:
Pain
Redness
Swelling
Fatigue
Headaches
Arthralgia (joint inflammation)
Myalgia (muscle inflammation)
Shivering
Sweating
Swollen lymph nodes
Fever
Vomiting
Tingling or numbness of the hands or feet
Shortness of breath
Vasculitis (inflammation of the blood vessels)
Serious adverse reactions are as follows:
Blood and lymphatic system disorders (lymphadenopathy)
Psychiatric disorders (insomnia)
Nervous system disorders (dizziness, paraesthesia, inflammation
of the central nervous system, inflammation of nerves,
autoimmune disorders affecting myelin sheaths of nerves
such as Guillain-Barré Syndrome)
Ear and labyrinth disorders (vertigo)
Respiratory, thoracic and mediastinal disorders (dyspnoea)
Skin and subcutaneous tissue disorders (pruritus, rash)
Musculoskeletal and connective tissue disorders (back
pain, musculoskeletal stiffness, neck pain, muscle spasms,
pain in extremity)
General disorders and administration site conditions
(bruising, asthenia, chest pain, malaise)
Disturbing Concentrations of Squalene
The average quantity of squalene injected into the US soldiers abroad
and at home in the anthrax vaccine during and after the Gulf War
was 34.2 micrograms per billion micrograms of water. According to
studies, this was the cause of Gulf War syndrome in 25% of 697,000
US personnel at home and abroad.
The soldiers developed a cascade of reactions including arthritis,
fibromyalgia, lymphadenopathy, rashes, photosensitive rashes, malar
rashes, chronic fatigue, chronic headaches, abnormal body hair loss,
non-healing skin lesions, aphthous ulcers, dizziness, weakness,
memory loss, seizures, mood changes, neuropsychiatric problems,
anti-thyroid effects, anaemia, elevated ESR (erythrocyte sedimentation
rate), systemic lupus erythematosus, multiple sclerosis, ALS, Raynaud’s
phenomenon, Sjorgren’s syndrome, chronic diarrhea, night sweats
and low-grade fever.
The AS03 adjuvant in the Arepanrix H1N1 vaccine contains 10.69mg
per dose. This corresponds to approximately forty times more squalene
per dose than the anthrax vaccine.
How much more evidence is necessary to convince public health officials
that the risks of the Arepanrix H1N1 vaccine exceed any benefits?
Please do not play roulette with your health. Do not listen to the
Public Health Agency of Canada or any public health or medical official
that advises you to protect yourself from the flu with this vaccine.
Its design and toxicity will only destroy your health.
Doctors speak out about H1N1 VACCINE DANGERS
Arepanrix
H1N1 Vaccine .pdf Exposed
Dave Mihalovic is a Naturopathic Doctor who specializes in
vaccine research, cancer prevention and a natural approach to
treatment.
