How The Tribune Undermines Antioxidants
Unprincipled science and medical reporting are not difficult to
come by these days. We are exposed to an epidemic of disgraceful
and negligent reporting, yet much of the general public is still
oblivious. While unprincipled reporting is nothing new, what is
new is the increasing frequency and degree of misleading information
and outright disinformation, which is skillfully presented to manipulate
public thinking into accepting the empty scientific
rhetoric of powerful science and medical institutions.
On the front lines of this battle for your mind, unrestrained
organized efforts of major media are employed to discourage the
public from investigating principled scientific research and alternative
approaches in health care. Their intimidation and obstructive
tactics include ridicule, discrediting, lying, deception, and
selective media coverage. Their concern is that if people were
to be presented with accurate scientific evidence on health issues,
they would soon realize much of what they thought to be real science
was, in fact, only an image of scientific authenticity. The vital
role of major media is to preserve that image.
Not surprisingly, Medical and Science reporter Trine Tsouderos
exemplifies this role as one of major medias perpetrators
of scientific integrity and truth with her latest piece of intellectual
poverty titled OSR#1:
Industrial Chemical or Autism Treatment? Unfortunately, this
type of disgraceful reporting is what most of us have come to
expect from todays biased journalism. It is
junk food journalism guaranteed to tantalize the nerve buds within
the minds of the uninformed and those who lack analytical thinking.
The Tsouderos style of journalism is easily recognized
by her unprincipled, relentless attacks against ethical researchers
and doctors who stand by the integrity of sound science and their
clinical results. Not exempt, her capacity for degeneracy also
extends to bashing parents utilizing alternative approaches, dietary
supplements, websites, such as Age of Autism, or any autism support
organization that provides accurate scientific information and
research analysis. When the battery of disparaging comments are
not enough she will then rebuke them with the sacred words established
by the false prophets of The Science she worships:
The Science says
However, with regard
to vaccines, autism, alternative approaches and dietary supplements,
The Science is riddled with black holes of willful
ignorance, insidious assumptions, false evidence, contrived statistics,
billions in special interest investments and large financial remunerations
for the players.
Relevant questions I pondered about Trine Tsouderos were: How
did she escalate from food and restaurant columnist magnifique
to crack Medical and Science reporter; and how did she suddenly
become an authority on OSR#1, chelation, autism and vaccines?
Could it be she operates in collaboration with undisclosed biased
personal connections with an agenda? Investigative research posted
on the Age of Autism website by beyond
disgusted provides some insight. Here are partial quotes:
William Egan, former vaccine chief at the FDA who
attended Simpsonwood, defended thimerosal to two House Committes
on Government Reform, and served on the CDC's Advisory Committee
on Immunization Practices while children's vaccines contained
Connect just a few dots: Trine's sister, Danielle, has
co-authored several studies with the FDA's Robert Ball who was
the lead author in one of those studies. This is the same Robert
Ball who acknowledges and thanks Egan in his "No Evidence
of Harm" Pediatrics article about thimerosal. Egan later
presented that paper WITH Ball at an IOM Workshop.
Danielle [Danielle Emig, MPH] is not only in public health,
but her senior research associate, Robert Ball, is an ardent and
vocal defender of thimerosal in vaccines.
Could this explain Tsouderos miserable disposition toward
OSR#1, Boyd Haley, Ph.D., and alternative health care?
With respect to Tsouderos assault on the safety and efficacy
of OSR#1 and the integrity of Boyd Haley, Ph. D., I felt compelled
to present the facts conspicuously absent and misconstrued in
Tsouderos drivel seeing as I am quite experienced with chelation,
OSR#1, its clinical applications, and acquainted with Boyd Haley,
First, for Tsouderos to classify OSR#1 an industrial chemical
is simply a combination of stupidity and gross ignorance, if not
intentional misrepresentation. Like other compounds used for industrial/agricultural
and human purposes such as EDTA (biological chelator), acetic
acid (commercial vinegar), ammonium chloride (gastrointestinal
acidifier/digestive aid), rat poison (drug Coumadin/Warfarin),
etc., there is a vast difference between the manner in which these
materials are synthesized and purified for human consumption.
The following is Dr. Haleys detailed explanation, which
Tsouderos conveniently overlooked:
OSR#1 is made under cGMP [code of Good Manufacturing Practice]
conditions and purified and synthesized in a manner similar to
the Atwood patent [the agricultural product], but using a quite
different process to make a pure product. Our purification process
produces a product that is over 99.9% pure compound. The Atwood
process does not. This is important for passing as a pure dietary
product. For example, EDTA is FDA approved for treating lead toxicity
is also used as an industrial compound to prevent calcification
of equipment. The difference between the two is that one is made
under stringent cGMP conditions as required by the FDA to insure
purity and safety. With cGMP synthesis we have to use the purest
starting materials and monitor each step with two chemists present
signing off on all the analytical steps and sending the finished
product for both purity and confirmation of structure. We have
spent hundreds of thousands of dollars confirming the lack of
toxicity of OSR and its antioxidant properties and efficacy. The
industrial process does not have these restrictions or requirements.
Second, Tsouderos made several statements undermining the publics
perception of the safety and efficacy of OSR#1, emphasizing erroneous
information and speculating OSR#1 was not properly and thoroughly
tested for human consumption. Tsouderos stated that, The
Food and Drug Administration told the Tribune that Haley had not
submitted sufficient information explaining how his new
dietary ingredient could be reasonably expected to be safe.
According to Dr. Haley, We submitted a huge amount of animal
safety data where OSR#1 was found not to be toxic at levels
several thousand times higher than what would be recommended
for humans, and the fact that OSR#1 was tested and found
not to be mutagenic. However, the FDA never even
mentioned this data in their response letter. The legal
code they listed as implying OSR#1 may be adulterated
had as its line that OSR#1 was not tested on humans.
This is a Catch 22 how could we test it on humans
before we did the 75 day premarket notification submission?
Immediately after the premarket submission Dr. Haley went on
to fund a 10 person study where over 200 blood/urine tests were
performed at 0, 30, and 60 days on OSR#1. Dr. Haley said, We
looked at everything, including OSR#1s effect on essential
minerals. This project was done on the relatives (children, parents,
spouses) of two medical doctors who also treat autistic children,
as well as older individuals, and whose children also had ASD
problems. No blood or urine test indicated any adverse effect.
However, the glutathione results improved dramatically. We obtained
an IRB (Institutional Review Board) to evaluate these results
and this also showed no adverse effects of OSR#1.
Tsouderos then ensued with negative criticisms by select experts.
First, environmental expert Ellen Silbergold commented how the
use of OSR#1 as a supplement for children was appalling.
This was followed by pharmacologist and antioxidant expert Dr.
L. Jackson Roberts expressing concern about any supplement given
to a small child that hasnt been scrutinized for both
safety and efficacy by the FDA. Apparently, Tsouderos never
made them aware of the safety and efficacy studies already conducted,
as Dr. Haley explained in his interview.
Tsouderos mentions the interview stating, In an interview,
Haley said that the compound had been tested on rats and that
a food safety study was conducted on 10 people. Asked to provide
documentation of the studies, he stopped communicating with the
Tribune. Of course, this was phrased to cast clouds of skepticism
upon the safety and efficacy of OSR#1, as well as to discredit
Haley. However, the reason for refusing to release the studies
to the Tribune is because of their obvious contempt toward him
and OSR#1. It was his intention to protect the reputations of
the medical physicians involved in the trials from being scandalized,
just as the Tribune has attacked other physicians in the past
for treating autism and implementing alternative approaches. Dr.
Haley would be pleased to release the IRB approved results to
Then the question was brought up: is OSR#1 an antioxidant or
a chelator? The answer: it is both. Here again, Tsouderos introduced
sufficient misinformation to create the perception that all chelators
are drugs and carry significant risks, which are certainly not
true. Some drug chelators, such as DMPS, do carry significant
risks, and I am not an advocate of DMPS. The fact is there are
many antioxidants that also act as chelators such as glutathione,
citric acid, products of the Krebs cycle, certain amino acids
and other dietary supplements with free sulfur group(s) that carry
metal chelating properties without risk. OSR#1 is simply a more
effective antioxidant and chelator. Its uncharged nature strongly
binds to specific heavy metals, such as mercury, cadmium, lead
and renders them harmless to the body. Dr. Haley never concealed
that fact. Also, OSR#1 has no affinity for essential elements
such as calcium, magnesium, and manganese; and food safety studies
indicated it did not decrease the levels of other essential metals
such as zinc, copper and iron.
Although Tsouderos, the champion of insidious assumptions, advocates
the influence of toxic metals as wild theory, pseudoscience
and nonsense without scientific evidence of an autism connection,
consider this: the EPA limit for mercury in drinking water is
2 ppb (parts per billion); mercury destroys neurite membrane structures
(connections between nerve cells) at 20 ppb; the EPA classifies
mercury-containing liquids as hazardous waste at 200 ppb; and
the current preservative level of mercury in the multi-dose vial
flu vaccine is 50,000 ppb! Even the reduced-Thimerosal flu vaccine
containing 0.0002% mercury
is equivalent to 2000 ppb 10 times the EPAs hazardous
waste classification! To independent thinking minds not associated
with the FDA, CDC, AAP and Big Pharma, these are irrefutable facts
implicating mercury as a valid cause of vaccine-induced autism;
as such, OSR#1 offers valid practical application.
On that note; Dr. Arthur Grollman, pharmacologist and director
of the Laboratory for Chemical Biology at State University of
New York at Stoney Brook, stated that toxic metals related to
autism are scientifically unfounded, and chelation
offers no benefits. How is it possible that an expert
in the study of biological systems is unable to comprehend that
mercury is a biological disaster? Does willful ignorance compel
Authentic scientific research has demonstrated that low
level mercury exposure can turn off specific sets of receptors
within the central nervous system and initiate a molecular chain
reaction that causes the cells to shut down and stop dividing.
Essentially, this study illustrates biochemical and resulting
neurodegenerative processes bearing an unmistakable resemblance
to the neurological regression observed in ASD children.
Dr. Haley, however, makes no claims to its chelating property
for the reason that the FDA is not concerned about what the compound
is, but what he claims it is in his advertisement. Dr. Haley commented,
OSR#1 is a combination of two natural products (benzoates
found in cranberries and cysteamine found in all mammalian cells
and a component of Co-enzyme A) with excellent ORAC test scores
(demonstrates excellent scavenging of free radicals); OSR#1 is
without detectable toxicity in test animals at high levels and
in human at lower levels. OSR#1 has pharmacokinetics that show
it penetrates all cells of the tissues of the body tested and
is effectively secreted within 24 hours. OSR#1, when added to
human liver homogenates and the resulting metabolites evaluated
by mass spectrometry shows the first two major products produced
are OSR#1 with two and three oxygen atoms attached, as expected
for a free radical scavenger.
OSR#1 is strictly marketed for its antioxidant property with
studies proving its ability to increase glutathione levels. For
Dr. Roberts to assert that it is absurd to believe
OSR#1 scavenges hydroxyl free radicals begs the question as to
how the Tribune phrased their question to him; or is he just incompetent
in antioxidant chemistry? Any chemist looking at the structure
of OSR#1 could recognize that it has two sulfhydryl groups very
similar to glutathione. Glutathione is the master antioxidant
of the body.
With respect to the question about why Dr. Haley changed the name
of his company from Chelator Technologies, Inc. to CTI Science,
it was to ensure nothing would be suggestive to the effect that
OSR#1 was marketed as a chelator. Dr. Haley has completely followed
FDA regulations, completed extensive safety and efficacy studies
and, most importantly, has provided an extremely safe and beneficial
dietary supplement with the potential to reduce oxidative stress.
Thats the real story.
Stephen C. LHommedieu, DC resides in Wichita, Kansas.
His practice, Advanced Alternatives for Health, specializes in
many difficult to treat health conditions. His clinical expertise
is in developing safe and effective methods for treatment of toxic
metals and chemicals. These he considers being the most insidious
substances to human health, and a component of all chronic health
issues, such as allergies, asthma, autism, etc. He has the ability
for uncovering and explaining the unexplainable underlying reasons
behind complex health disorders.
February 12, 2010