Scientists from Germany, Finland and Denmark report that daily coffee consumption was associated with improved cholesterol levels and blood levels of inflammatory compounds such as interleukin-18.
“Our study represents the first intervention trial to investigate the anti-inflammatory effect of coffee and to develop and test coffee-derived compounds in plasma as biomarkers of coffee intake during long-term coffee consumption,” stated the researchers, led by Christian Herder from Heinrich Heine University Dusseldorf.
Writing in the American Journal of Clinical Nutrition, the European scientists also note: “Coffee consumption appears to have favourable effects on some markers of subclinical inflammation and oxidative stress and to increase plasma concentrations of potential biomarkers of coffee intake.
“Because subclinical inflammation is a risk factor for type 2 diabetes, our results suggest one mechanism that could mediate the reduced risk of type 2 diabetes among individuals who habitually consume coffee for years.”
Coffee and its extracts
The beverage, and its constituent ingredients, has come under increasing study with research linking it to reduced risk of diabetes, and improved liver health.
Coffee, one of the world's largest traded commodities produced in more than 60 countries and generating more than $70bn in retail sales a year, continues to spawn research and interest.
Indeed, a recent report by Mario Ferruzzi from Purdue University in Physiology & Behavior (doi: 10.1016/j.physbeh.2010.01.035) stated that coffee is one of the richest sources of polyphenols in the Western diet, with one cup of the stuff providing 350 milligrams of phenolics. Of these, the most abundant compounds coffee are chlorogenic acids, making up to 12 per cent of the green coffee bean. The most abundant of these compounds is caffeic acid.
The new study, supported financially by the Institute of Scientific Information on Coffee, which is a consortium of major European coffee companies, involved 47 regular coffee drinkers. The participants stopped drinking the beverage for one month, then llimited themselvs to four cups a day for another month, and then drank eight cups per day for a third month.