The makers of Fixodent are being sued over allegations that the popular denture adhesive causes nerve damage.
The product contains zinc, which lawyers representing former users in the class action in the U.S. blame for their neurological illnesses.
Fixodent is widely used in Britain, where the formula also contains small amounts of zinc to help give the adhesive more grip.
Anne Coffman, one of the plaintiffs in the American action against makers Procter & Gamble, claims the product caused numbness in her limbs.
The 48-year-old was diagnosed with zinc poisoning, a condition in which high levels of the metal interfere with the body’s absorption of copper, which can lead to irreversible nerve problems.
‘Fixodent is the only product that I’ve ever used that had zinc in it,’ she said.
Patient Mark Jacoby, 41, said he became increasingly unsteady on his feet and ended up in a wheelchair after using the product.
Doctors eventually tied his disorder to high levels of the mineral zinc in his body.
Mr Jacoby, who has worn dentures for 20 years, said he believed the contamination came from his denture cream, which he has now stopped using.
'I can almost guarantee you it was the Fixodent. It's soaked into your body and it messes with the nerves,' he told ABC News.
A connection between the adhesive and neurological disease was made in a study reported in the journal Neurology in 2009.
Researchers at the University of Texas said they found all four denture users had high zinc levels that could measured in the blood.
Its publication was delayed for two years after Dr Kenneth Shay released a peer review who said the study was 'little more than speculation.'
However, an ABC News investigation has since found that Dr Shay was a paid consultant for Procter & Gamble when he reviewed the study. Dr Shaw told ABC New he defended his review saying the report had 'objective shortcomings.'
There have been previous alerts linking denture users with neurological disease.
In 2009, Procter & Gamble added a warning label to its Fixodent packaging, saying that ‘prolonged zinc intake may be linked to adverse health effects’.
Procter & Gamble said: ‘Our Fixodent formula has undergone extensive testing. We know of no valid scientific evidence that using Fixodent as directed causes any ill health effects.’