Published in the Journal of Agricultural and Food Chemistry, the reviewsuggests that following a vegan lifestyle that is low in omega-3 and vitamin B12, may have a high risk of developing blood clots and atherosclerosis – both of which increase the risk for heart attacks and stroke. As such, the authors suggest that an increased intake or supplementation of omega-3 polyunsaturated fatty acids and vitamin B12 may help to alleviate such risks.
“On the basis of the present data, it is suggested that vegetarians, especially vegans, could benefit from increased dietary intake of omega-3 PUFA and vitamin B12 and thus improve the balance ratio of omega-3 to omega-6 PUFA and vitamin B12 status … which may reduce any thrombotic tendency that might increase their generally low risk of cardiovascular disease,” said the review author, Duo Li from Zhejiang University, China.
The review of over 30 years of studies for the biochemistry of vegetarianism noted that meat-eaters are known to have a significantly higher incidence of certain cardiovascular risk factors compared with vegetarians.
Such risks include increased body mass index, waist to hip ratio, blood pressure, plasma total cholesterol, triacylglycerol levels, and serum lipoprotein concentration.
However, Li said that compared with meat-eaters, vegetarians and vegans have lower concentrations of serum vitamin B12 and omega-3 polyunsaturated fatty acid levels in tissue membrane phospholipids.
Previous evidence has suggested vegetarians and vegans who do not take vitamin B12 supplements often may have abnormally low serum concentrations of vitamin B12, which has been shown to significantly correlate with plasma homocysteine levels.
Li said that the risks associated with low vitamin B12 and omega-3 status include increased collagen and homocysteine levels and decreased levels of ‘good’ HDL-cholesterol – all of which may be linked to an increased thrombotic and atherosclerotic risk.
As a result Li concluded that “it is suggested that vegetarians, especially vegans, should increase their dietary omega-3 PUFA and vitamin B12 intakes.”
Despite the fact that vegan diets exclude any foods from animal origin, in his recommendations Li outlined several sources of dietary omega-3 and vitamin B12 sourced from animals; though he did add that “dietary supplements also can supply these nutrients”.
Source: Journal of Agricultural and Food Chemistry