If you don't get enough vitamin E in your diet, you
may have a greater risk of declining physical function
as you age, according to the findings of a new study.
Yale researchers
report that people with the lowest blood levels
of vitamin E have about 60 percent greater odds of a decline
in physical function when compared to people with the
highest levels of vitamin E.
"Low plasma levels of vitamin E are associated with
subsequent decline in physical function," said the
study's lead author, Benedetta Bartali, a nutritionist
and a Brown-Coxe postdoctoral fellow at Yale
University's School of Medicine.
"As an antioxidant, vitamin E may prevent or reduce
the propagation of free radicals in our body, and this
may help to reduce muscle or DNA damage and the development,
for example, of atherosclerosis and other pathologic conditions,"
Bartali said, although she added that this study wasn't
designed to identify the reasons why vitamin E might be
helpful.
Results of the study are published in the Jan. 23 issue
of the Journal
of the American Medical Association.
In the past, it was believed that vitamin E could help
prevent serious illness, such as heart disease or Alzheimer's.
However, more current research found that excess levels
of vitamin E, rather than being helpful, could actually
be harmful. For that reason, it's recommended that
people don't take more than 400 I.U.'s [International
Units] of vitamin E daily. And the recommended daily dose
is significantly lower than that -- 15 milligrams or 22.5
I.U.'s daily for anyone over the age of 15, according
to the U.S.
National Institutes of Health.
Because poor nutrition has been associated with physical
decline in older people, Bartali and her colleagues randomly
selected almost 700 adults over age 65 from an ongoing
longitudinal study in Tuscany, Italy. They reviewed blood
tests to ascertain vitamin levels and reviewed data from
physical function exams completed at the start of the
study and at the three-year follow-up.
After adjusting the data to account for other factors
that could contribute to physical decline, such as smoking
or a lack of physical activity, the researchers found
two factors were significantly associated with a greater
chance of experiencing physical decline -- age and low
levels of vitamin E. Levels of B vitamins, vitamin D and
iron didn't increase the odds of physical decline,
according to the study.
Being older than 81 years increased the odds of physical
decline by 84 percent, and low levels of vitamin E in
people between the ages of 70 and 80 increased the odds
of physical decline by 60 percent, according to the study.
"Because only one person in our study used vitamin
E supplements, our results suggest that an appropriate
dietary intake of vitamin E may help to reduce the decline
in physical function among older persons. Whether the
use of vitamin E supplements would yield similar beneficial
effects is unknown," Bartali said.
Dr. Kanwardeep Singh, a geriatric specialist at St. John
Hospital and Medical Center in Detroit,
said that while this is a very well-done study, it's
difficult to "take the effect of age out of what
we are trying to identify."
For now, he said, "I would not recommend vitamin
E supplements. My recommendations would be based on a
good nutritious diet, with adequate caloric intake and
adequate exercise. These will take you far beyond vitamin
E supplements" in maintaining physical function.