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Fibre 'Lowers Breast Cancer Risk'

Pre-menopausal women who eat large amounts of fibre could halve their breast cancer risk, a recent study has suggested.

The University of Leeds researchers, who studied 35,000 women, found those who ate 30g of fibre a day had half the risk of those who ate less than 20g.

They said women should try to increase their fibre intake.

Experts said the International Journal of Epidemiology study was more evidence of the benefits of a healthy diet.

To eat 30g, a person would need to eat a high-fibre cereal for breakfast, switch from white or brown bread to wholemeal and ensure they have five portions of fruit and vegetables a day.

A team from the University of Leeds Centre for Epidemiology and Biostatistics have been monitoring the eating habits and health of more than 35,000 women for seven years.

They were aged 35 to 69 at the beginning of the study.

Diet was assessed using a 217-item food questionnaire.

Processing

Unlike other studies looking at fibre intake and breast cancer risk, the women studied had a range of diets including groups who were wholly vegetarian or who did not eat red meat.

Just under 16,000 women were pre-menopausal when they entered the study, with 18,000 post-menopausal.

257 pre-menopausal women developed breast cancer during the study, which was initially funded by the World Cancer Research Fund.

They were found to be women who had a greater percentage of energy derived from protein, and lower intakes of dietary fibre and vitamin C, compared to women who did not develop cancer.

However, the effect was not seen in the post-menopausal group, in which 350 developed breast cancer.

The researchers say this may be because fibre affects the way the body processes and regulates the female hormone oestrogen.

Levels of the hormone are higher in pre-menopausal women.

Early exposure

Professor Janet Cade, who led the research, said: "Our study found no protective effect in the older group, but significant evidence of a link in the pre-menopausal women.

"The relevant exposure may be earlier in life, explaining why the protective effect was not shown in the post-menopausal group."

She added: "In addition, post-menopausal women with high body mass indexes [who are overweight or obese] have an increased risk of breast cancer.

"Their weight may over-ride any other effects such as benefits from fibre."

Professor Cade added: "It goes along with the general healthy eating advice to make sure that you are getting plenty of fibre in your diet through breakfast cereals, bread, pasta, fruit and vegetables."

Ed Yong, cancer information officer at Cancer Research UK, said: "We already advise eating a diet rich in fibre to reduce the risk of bowel cancer. "This study suggests that it could help protect against breast cancer in younger women too."

He added: "Until now, the evidence that fibre could reduce the risk of breast cancer has been inconsistent.

"This study suggests that this is because any protective effects are limited to women before their menopause.

"It further highlights the importance of eating a healthy diet for reducing the risk of cancer."

Dr Sarah Cant, of the charity Breakthrough Breast Cancer said separating out the individual effects of different food was difficult.

Reference Source 108
January 24, 2007

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