A booster shot against hepatitis B may not be necessary
because infants and teens who are vaccinated against hepatitis
B are protected for 10 years after the vaccination, according
to Italian researchers.
Viral hepatitis B is the leading cause of acute and chronic
liver disease worldwide. About 2 billion people around the
world have been infected with hepatitis B, says the World
Health Organization. Currently, 168 countries have universal
infant or adolescent hepatitis B vaccination programs.
Until now, it wasn't clear if vaccinated children needed
booster shots to sustain their immunity to hepatitis B infection.
Reporting in this week's issue of The Lancet, the
researchers studied whether concentrations of antibodies
against hepatitis B were still present in 1,212 children
and 446 Italian Air Force recruits who received hepatitis
B vaccinations as infants and adolescents, respectively.
The study found that 64 percent of the children and 89
percent of the recruits still had protective concentrations
of antibodies. The results indicate that infant and adolescents
immune systems can recall responding to hepatitis B more
than 10 years after immunization.
"In light of our findings, the use of routine booster
doses of hepatitis B vaccine does not seem necessary to
maintain long-term protection in immunocompetent individuals
vaccinated as infants and teenagers," researcher Alessandro
Remo Zanetti of the Institute of Virology in Milan, said
in a prepared statement.