Moderate drinkers have lower rates of heart disease, as
research has shown, but they may have a price to pay: Alcohol
can thin the blood, perhaps increasing the risk of bleeding
strokes.
That's the finding from a study published in the October
issue of Alcoholism: Clinical & Experimental Research.
Study author Dr. Kenneth Mukamal, a researcher at Beth
Israel Deaconess Medical Center, in Boston, found that alcohol
intake thins the blood, which is good for preventing clots
that can lead to heart attacks but not good when it comes
to the risk of bleeding strokes.
"The contrasting effects of alcohol are similar to the
effects of blood thinners like aspirin, which clearly prevent
heart attacks but at the expense of some additional bleeding
strokes," Dr. Mukamal said in a statement.
In the study, Mukamal's team evaluated more than 3,000
participants in the Framingham Offspring Study, which looked
at risk factors for cardiovascular disease. The study, began
in 1971, included the sons and daughters of participants
in the Framingham Heart Study, which began in 1948.
"There has been a lot of circumstantial evidence over the
years that alcohol consumption is both good and bad," said
study co-author Dr. Kenneth Ault, director of the Research
Institute at the Maine Medical Center, in Portland. "The
simple story is that moderate alcohol consumption is protective
for a lot of cardiovascular problems."
The new study confirms previous evidence, Ault said, suggesting
that alcohol is often beneficial but may have a downside.
The new study focused on platelets, small particles in
the blood that contribute to clotting, Ault explained. It
evaluated how fast they start the clotting process, known
as "activation," and how much they clump together, known
as "aggregation" or "stickiness." Previous research has
shown that moderate drinkers tend to have less sticky platelets
than nondrinkers.
"In men, both activation and aggregation went down with
moderate drinking," Ault said. Moderate drinking was considered
to be three to six drinks a week or more.
"In women, only aggregation went down. But I wouldn't make
a big deal of that," said Ault, explaining the finding could
have been a statistical fluke.
Another expert, Dr. Marc Siegel, an associate professor
of medicine at New York University School of Medicine, said
the study was "fairly well-done."
"The bottom line is alcohol has a plus and a minus," he
said, and the new study "puts the two things together, and
give you more clinical wisdom."
The message to consumers? "Don't start thinking of alcohol
as a panacea," Siegel said. "Even if there is some benefit,
there is a cautionary flag. A drink a night is generally
believed to cut the risk of heart disease, but it is hardly
medicinal. And this study reminds you of that."