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Alcohol
Damage Continues
After Drinking Stops
(HealthScoutNews)
-- Even after alcoholics stop drinking, they continue to experience
motor problems.
A Vanderbilt University Medical
Center study also found the brains of abstinent alcoholics seem
to compensate for alcohol-caused brain damage by using other brain
regions.
The study, published in the April
issue of Alcoholism: Clinical and Experimental Research,
included seven males and one females, all of whom were alcohol-dependent
but didn't have any alcohol for two weeks. They were compared
to seven female and two male healthy volunteers in a control group.
All the participants performed
finger-tapping exercises while the researchers used functional
magnetic resonance imaging (fMRI) to observe the brain regions
that were used in the exercise.
Both groups alternated between
their dominant hands and non-dominant hands to do the finger-tapping.
The alcohol-dependent people performed
the finger-tapping much more slowly than those in the control
group. However, that slower finger tapping wasn't accompanied
by proportionately decreased fMRI brain activity in the cerebral
cortex and cerebellum, the brain regions involved in this kind
of motor function.
Instead, the researchers observed
that the alcoholic-dependent people showed a significant increase
of activity in the cortical brain region on the same side as the
hand that was doing the finger-tapping.
That means the alcoholics had to
use more of their brains to do less in terms of performing a simple
motor skill, compared to the control group.
The study findings pose new questions.
"If we study patients as they
progress with the abstinence, do these abnormalities get better?
It may be that the brain gets better at compensating, but it doesn't
normalize. It just learns how to bring in even more parts of the
brain. You could say it learns to rewire itself," Peter R.
Martin, a professor of psychiatry and pharmacology and corresponding
author for the study, says in a news release.
"Another possibility could
be that as the brain heals, less activation is required, and that's
a real form of recovery. The answers rest with understanding not
the tapping itself, but the mechanisms behind the tapping,"
Martin adds.
More information
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