Anti-Impotence
Cream to Take on Viagra
Excerpt
By Brian Walker, Reuter's
Health
HONG KONG (Reuters) - The world's first topical treatment for
erectile dysfunction has been unveiled in Hong Kong, giving an
intriguing new treatment option to impotence sufferers.
The new medicated cream, branded "Befar," promises a safer and quicker
treatment for impotence than Viagra.
After quietly selling the drug in China since last July, NexMed,
a small biotechnology company based in New Jersey says it is ready
to bring the medicated cream to the rest of Asia, and eventually
the US.
Befar uses the active ingredient Alprox-TD, a derivative of
alprostadil, developed by NexMed. Alprostadil has been used to
treat erectile dysfunction for several years around the world,
but until now has been administered via injection directly into
the penis.
"The drug has been proven very effective, but it was just too
painful to apply because you have to inject (it)," Dr. T. Tom
Wu, managing director of NexMed (Asia) Limited told Reuters Television.
"We are the first non-invasive drug that is very user-friendly."
Alprox-TD works by widening the blood vessels in the penis,
allowing it to be engorged with blood. But users of Alprostadil
have reported side effects including persistent erection, known
as priapism, in which erections can become painful after lasting
several hours.
NexMed claims that clinical tests in the US have shown that
83% of men suffering erectile dysfunction reported satisfaction
with the topical treatment. Alprox-TD also reportedly begins to
cause erection within minutes, much faster than many alternatives.
But urologist Dr. Peter Chan Siu Foon of the Chinese University
in Hong Kong notes that onset times for reactions to topical treatments
can be difficult to predict, but actually may be conducive to
better sex.
"Sex and lovemaking is not a mechanical event, so to wait half
an hour is not such a bad thing and can lead couples to focus
on foreplay which will enhance their love life," Chan said.
Many new medicines are scrambling to get into the burgeoning
anti-impotence drug marketplace in the next few months. NexMed
is hoping to get a headstart on the competition by getting into
niche markets like China now and moving into bigger marketplaces
like the US later.
"For an independent pharmaceutical, it really makes sense for
us to try to get registered in a territory that we think it will
be accepted," said Wu. "Since it's an old drug with a new application,
it's much easier to receive approval."
The company says that Befar provides several key health and
convenience benefits that should help it compete with industry
titan Pfizer Inc.'s Viagra.
As a topical lotion it should hold less risk of interacting
with other ingested medicines. Because it is applied directly
to the penis, NexMed also claims that it works within minutes
rather than the hour or so it can take Viagra to take effect.
NexMed is now beginning phase III clinical development testing
for Alprox-TD in the US, and is also completing study of a similar
product for women called Femprox, aimed at treating female sexual
arousal disorder.
Reference
Source 89
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