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Arthritis Outlook Worse for Women
Excerpt
By David Douglas, Reuters Health
Both women and men with early rheumatoid
arthritis improve rapidly with treatment, but ultimately women
fare worse than men, new research from Sweden suggests.
Rheumatoid arthritis is a chronic
disease that involves inflammation of the joints, resulting in
pain and decreased mobility. The exact cause is unknown, but it
is classified as an autoimmune disease--meaning that the patient's
own body is actually attacking itself.
Drug therapy is effective at limiting
joint damage in patients newly diagnosed with rheumatoid arthritis,
Dr. Thomas Skogh told Reuters Health. Unfortunately, these patients
still experience a decline in their functional abilities over
time, he added.
In his study, men had joint disease
that was equal to, if not worse than, that of women, Skogh noted.
Still, men showed "signs of more pronounced improvement and a
more favorable course than the women with regard to functional
abilities," he said.
Skogh, from the University of Linkoping,
and colleagues came to these conclusions after following 284 patients
with early rheumatoid arthritis. The severity of their disease
was gauged by a number of factors and a special questionnaire
was given to the patients to determine their functional ability.
The new findings are reported in
the Annals of the Rheumatic Diseases.
Disease severity improved in all
patients during the first 3 months of treatment, but then it leveled
off. At 1 year, the patients began to notice a drop in their functional
abilities.
When the study began, men and women
were equal in terms of functional ability. However, when they
were tested again 1 and 2 years later, women had experienced a
greater drop in their abilities than men.
"The reasons for this are not obvious,"
Skogh concluded, "but may reflect a more aggressive disease course
in women."
SOURCE: Annals of the Rheumatic
Diseases July 2003
Reference
Source 89
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