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Do
More Calories Help
Colon Cancer Patients?
Excerpt
By
Adam Marcus,
HealthScoutNews
High-calorie diets may actually protect you in a battle with colorectal
cancer.
That's the surprising result of
a new study from French scientists, who say that energy intake
before a diagnosis of colorectal cancer predicts the odds of surviving
the disease over time. Why eating more benefits these people isn't
clear, however, and some experts aren't convinced the link is
real. A recent study from the American Cancer Society found that
being overweight or obese raises the risk of dying from any cancer,
including colorectal tumors, by between 50 percent and 60 percent.
But study author Dr. Marie-Christine
Boutron-Ruault believes people who eat more may develop a less
aggressive form of colorectal tumors than do people whose diets
are lower in calories. "We are going to follow up this idea
by studying the genes of tumors" in patients with high and
low energy intake, says Boutron-Ruault, a nutrition researcher
at French Institute of Health and Medical Research in Paris.
Boutron-Ruault and her colleagues
report their findings in the June issue of Gut. The researchers
looked at 148 elderly men and women, whose average age was 64,
who had undergone surgery to remove colorectal cancer. Subjects
were asked to recall how much they ate before they were diagnosed
with the disease.
The strongest predictor of a patient's
risk of death over the 10 years after surgery was how advanced
their disease was at the time of the operation.
Yet diet also appeared to play
a role. People in the bottom two-thirds of daily energy intake
were about 80 percent less likely to be living five years after
surgery than those in the upper third of energy intake -- above
roughly 3,000 calories a day for men and 2,300 calories a day
for women. Although that amount of food is unusually high, especially
for the elderly, not everyone in this group was obese, nor did
being overweight seem to affect the results.
Since the study relied on people's
memories of their diets, it used an imperfect measure of energy
intake. What's more, the findings could simply be showing that
people with less aggressive forms of colorectal cancer are able
to eat more than those with deadlier tumors.
Martha Slattery, an epidemiologist
who studies diet and cancer at the University of Utah School of
Medicine in Salt Lake City, says the findings raise a "big
red flag" in light of research linking obesity to a greater
risk of developing colorectal cancer. "The two don't go together,"
says Slattery, who has looked at the issue.
What may explain the French results,
she says, is if people who eat more are generally healthier than
those who eat less. That could make them more prone to colorectal
cancer, and presumably other tumors that become more likely with
age.
In an unrelated study also published
in Gut, Danish researchers say heavy drinking seems to
raise the risk of rectal tumors, but not colon cancer. However,
people whose tippling included at least 30 percent wine, while
still at increased risk, cut their chances of rectal cancer significantly
compared with beer and liquor drinkers.
More information
For more on colon cancer, visit
the American
Cancer Society or the National
Cancer Institute.
Reference
Source 101
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