Can Mammograms Spot Heart Disease?
(HealthScoutNews) -- Mammography makes
headlines as a screening test for breast cancer, but the technology
may do double duty as a predictor of heart disease.
Women whose mammograms spot calcium
deposits in their breast arteries are more vulnerable to heart
attacks and other fallout of cardiovascular disease than those
with clean vessels, new research has found. While the calcifications
in the breast don't harm the heart, they appear to echo narrowing
of the coronary arteries that feed the pump.
"Most people don't worry about
[the deposits] because they're not cancer," says Dr. Kirk
Doerger, a radiology resident at the Mayo Clinic and a collaborator
on the research. "But now we're finding that they do have
some importance."
In 1998, for example, Dutch doctors
found that women with calcified breast arteries faced a sharply
higher risk of cardiovascular death, especially if they had diabetes.
And last year, Israeli scientists also found the deposits, which
increase with age, upped the risk of cardiovascular disease in
women -- enough to lead the researchers to conclude that mammography
might be a cheap and effective screening tool for heart and vessel
problems.
However, the latest study can't
make so strong a statement, says Doerger, who presented the findings
today at the Radiological Society of North America's annual meeting
in Chicago.
Doerger and his colleagues reviewed
medical records of 1,803 women who'd had mammography as well as
angiograms to examine their coronary arteries. They found that
after adjusting for a woman's age -- which is tightly linked to
cardiovascular illness -- the presence of breast artery calcifications
on mammograms increased the risk of significantly narrowed blood
flow to the heart by 20 percent.
Smoking raised that risk by 50
percent, and diabetes drove it up 210 percent, Doerger says, so
the effect is on the modest side. Still, he adds, "it's free
information" that radiologists now ignore.
Each breast has three main arteries
supplying blood. Calcifications on at least three of those vessels
raised the risk of coronary artery blockage, Doerger says. However,
more extensive breast artery lesions didn't magnify that risk,
he says.
Turning mammography into a tool
to detect heart disease underscores a common misperception about
women's health. While many women express more fear of breast cancer
than cardiovascular disease, it's the latter that's more likely
to kill them.
Heart disease kills nearly a half
million American women each year, more than all cancers combined.
And nearly two-thirds of women who suddenly die of heart problems
have no previous symptoms.
Still, Dr. Susan Orel, a radiologist
at the University of Pennsylvania School of Medicine, says she's
not sure what to make of the new research.
Since the women already had signs
of artery trouble, the study group was "very biased"
from the start, she says. What's more, "you see [calcification
of the breast vessels] almost all the time in older women,"
diluting the potential significance of the marker.
On the other hand, Orel adds, calcifications
on the mammograms of women in their 30s and 40s stir her concern.
What To Do
For more on women and heart disease,
try the American
College of Obstetricians and Gynecologists or the American
Heart Association.
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