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Diabetics Have a Much
Higher Risk of Death


NEW YORK (Reuters Health) - Diabetics--regardless of their age or income--are at much greater risk of dying during a given time period compared with those without the condition, UK researchers said on Thursday.

The mortality risk was greatest for those with type 1 diabetes, and even the most affluent diabetic patients had a greater risk of death than their poorer, non-diabetic neighbors, according to a study of diabetics living in northern England. The report is published in the June 9th issue of the British Medical Journal.

Overall, nearly one quarter of those with diabetes died during the 6-year study, a death rate more than twice the national average. A man or woman diagnosed with diabetes by the age of 40 had their life expectancy reduced by 8 years.

``The majority of the mortality was the result of vascular disease, for which proven, effective interventions exist,'' Dr. Nick A. Roper of Middlesbrough General Hospital in Middlesbrough, UK, told Reuters Health.

``The major message therefore is to increase the take up rates for interventions: smoking cessation, exercise, healthy diet, aspirin treatment, blood pressure treatment, cholesterol treatment and good blood glucose control.''

Type 1 diabetes, which usually is diagnosed in children or young adults, requires daily injections of the blood sugar-regulating hormone insulin for survival. Type 2 diabetes, which is more often diagnosed in adulthood, can sometimes be controlled with diet and exercise, although some people require oral medication or insulin shots to control blood sugar. In general, diabetes increases the risk of circulatory problems, blindness and heart disease.

In the study, the researchers looked at nearly 5,000 diabetics living in South Tees, in northern England, and followed them for 6 years, tracking their mortality rates. The investigators then compared those death rates to those among their non-diabetic neighbors and the rest of England and Wales.

The risk of death among the most affluent fifth of the diabetics was slightly higher than the death rate of those without diabetes. However, the death rate continued to rise significantly as the level of poverty increased. The poorest group of diabetic patients had more than twice the death rate of non-diabetics.

``The extent of the reduction in life expectancy was significant,'' Roper said.

The main cause of death among the diabetics was heart disease, leading the researchers to suggest that patients with those risk factors should be treated more aggressively.

In an accompanying editorial, Gareth Williams, a professor of medicine at the University Hospital Aintree in Liverpool, noted that the rise in type 2, or adult-onset, diabetes can be mainly attributed to obesity. Sadly, he writes, counteracting the growing ``obesity pandemic'' will be resisted by ``the manufacturers of cars, televisions, computer games, fizzy drinks and fast foods.''

SOURCE: British Medical Journal 2001;322:1389-1393, 1375-1376.

Reference Source 89

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