First
20 Years in Life Key to Cancer Risk
STOCKHOLM (Reuters) - Lifestyle during the first 20 years of
life is a more important factor than genetics when defining the
risk of cancer, two Swedish studies on first- and second-generation
immigrants show.
"Birth in Sweden sets the Swedish pattern for cancer development
irrespective of the nationality of descent," said the abstract of
one of the studies due to be published on May 10 in the International
Journal of Cancer.
The survey of some 600,000 immigrants, who came to Sweden in
their 20s and became parents in this country, showed that their
cancer risks did not differ significantly from the cancer risks
of the populations in their native countries.
But second-generation immigrants born in Sweden had a different
risk profile than their parents and had a similar cancer incidence
as native Swedes, another study of some 600,000 immigrants, mainly
from Europe and North America, showed.
"Internationally, there are clear differences between cancer
risks. But these differences disappear within one generation,
so environment must clearly be a significant cancer factor," Professor
Kari Hemminki of the Karolinska Institute university hospital
told Reuters Monday.
As the first 20 years of a person's life were so important in
defining the risk of incurring cancer, possible preventive means
should be aimed during that period, he said.
For some types of cancer it was clear why the risks were different
between the generation who spent their first 20 years outside
Sweden and their children born in Sweden.
For example, the risk of lung cancer decreased among second-generation
immigrants because Swedes tended to smoke less than people in
many other countries.
The higher risk of stomach cancer among first-generation immigrants
compared with their children and native Swedes could be linked
to eating habits, vitamin deficiencies and use of salt--all factors
linked to this type of cancer, Hemminki said.
Darker skinned second-generation immigrants were as prone to
contract skin cancer as blond Swedes, and much more so than their
own parents, due to a similar sun bathing style among youths regardless
of origin.
The studies were made using the Swedish Family Cancer Database,
which contains information on all people born in Sweden after
1931 and their parents.
Reference
Source 89
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