Food
Expert Predicts
'Nutrigenomics' Revolution'
Excerpt by E.J. Mundell, Reuters Health
CHICAGO (Reuters
Health) - A merging of genomics, nutrition and medicine may mean
that ``you are what you eat'' becomes ``you eat what you are,''
as consumers of the future tailor their grocery lists to their
DNA.
We are entering
``a new nutritional paradigm--the genetic era of nutrition,''
said nutritional science consultant Dr. Nancy Fogg-Johnson of
Life Sciences Alliance in Pleasanton, California. She outlined
the coming age of nutrigenomics in a speech presented here Tuesday
at the annual meeting of the American Chemical Society.
The recent
publication of the human genome--humankind's genetic ``blueprint''--has
triggered an explosion in research into how drugs might be individualized
to capitalize on each patient's unique genetic code.
But Fogg-Johnson
believes the line between food and drug is blurring in the era
of the genome. Consumers already make ''dietary choices based
on genetics,'' she pointed out--everything from a switch from
milk to soy for the lactose-intolerant, to cholesterol-lowering
spreads like Benecol and Take Control for those with a propensity
to heart and blood vessel disease.
The next step,
she said, is for industry to provide consumers with quick, cheap
methods of assessing their gene profiles so that they can use
them to make informed decisions about what they eat.
As an example,
Fogg-Johnson noted that individuals with just one mutation in
a specific gene might need a higher-than-average intake of folate-rich
foods, such as fortified breads, so that they could fully protect
themselves from heart disease. Having a copy of one's genetic
profile would alert consumers to these types of important aberrations.
Nutrigenomics
could become a central concern throughout the life span, she added.
Children could be tested for their DNA in infancy, to make sure
their diets put them on the road to lifelong health.
In fact, Fogg-Johnson
envisages the day when shoppers routinely hand over a copy of
their DNA sequence during every trip to the druggist or grocery
store. Food production and delivery could also be tailored in
a ``crop-to-fork'' way, with specific products aimed at groups
of consumers sharing the same genetic makeup.
Of course,
obstacles remain. Privacy issues over who owns an individual's
gene sequence will need to be addressed, and much needs to be
done to streamline technologies so that genetic testing becomes
more accessible and affordable.
But already,
the ``scientific continuums of nutrition and genomics have absolutely
merged,'' Fogg-Johnson said, noting that a few small US companies
now offer consumers genetic profiling. ``The technology to accomplish
this in an economically feasible, consumer-relevant way is becoming
a reality,'' she stated.
Reference
Source 89
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