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Herbal
Supplement Eases PMS Symptoms
NEW YORK (Reuters
Health) - An herbal extract used in ancient times to douse women's
sexual desire may serve a more modern purpose. The chasteberry,
also known as agnus castus, appears to relieve many of the symptoms
of premenstrual syndrome (PMS), German researchers report.
In a trial
comparing the effects of agnus castus supplements with an inactive
placebo, investigators found that the supplement significantly
reduced PMS symptoms such as irritability, headache, mood swings
and breast tenderness. Agnus castus is a flowering shrub, the
fruit of which is used for supplements.
Dr. Rudiger
Schellenberg and colleagues at the Institute for Health Care and
Science in Huttenberg studied 170 women with PMS. Over three menstrual
cycles, half of the women took agnus castus supplements, while
the rest received a placebo.
The supplement
turned out to be superior in relieving several common PMS symptoms,
according to a report in the January 20th issue of the British
Medical Journal. More than half of the women on agnus castus reported
a 50% or greater reduction in their symptoms, compared with 24%
of those on placebo.
While extract
of agnus castus is already a popular PMS treatment in Germany,
the supplement has rarely been studied in placebo-controlled trials,
Schellenberg told Reuters Health. Exactly why the supplement helps
is unclear, he said, but research suggests it regulates levels
of prolactin, a hormone that rises during pregnancy to stimulate
milk production. In non-pregnant women, elevated levels of prolactin
may contribute to breast pain and other PMS symptoms.
The other
advantage of agnus castus, Schellenberg noted, is that there appear
to be no significant side effects with the 20-milligram per day
dose used in the study. Four women on the supplement reported
mild side effects, while three women on placebo did.
The study
was funded by Zeller AG, which supplied the product and sponsored
the study through the Clinical Research Organization Praxis Klinische
Arzneimittelforschung in Polheim, Germany.
SOURCE: British
Medical Journal 2001;322:134-137.
Reference
Source 89
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