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High-Grain
Diet May Increase
Risk of Cardiovascular Disease
When
humans consume more carbohydrates than can be stored, the excess
carbohydrate energy is converted to fat by the liver. This process
may maintain blood sugar control and prevent diabetes in the short-term,
however it may also increase triglyceride concentrations, which
may increase the risk of cardiovascular disease.
In the last decade,
researchers established that fat production by the liver varies
depending on dietary habits and health status.
The typical Western
diet has a high fat content, which means that only a limited amount
of carbohydrates are available for liver fat production, and liver
fat production tends to be very low among individuals who eat
this type of diet. However, when too many carbohydrates were consumed,
both liver fat and sugar production were increased.
A very low-fat (10
percent of energy) and very high-carbohydrate (75 percent of energy)
diet also leads to increased liver fat production, with the increase
being even more pronounced when more than half of the carbohydrate
was consumed as simple sugars. This points to the importance of
carbohydrate quality, as another study using 68 percent of energy
from complex carbohydrate resulted in minimal liver fat production.
However, it was found
that obese individuals with high insulin levels who consume a
high-fat (40 percent of energy) diet had a liver fat production
rate three to four times higher than that of lean individuals
with normal insulin levels. But, both normal and high insulin
groups had lower liver fat production on the high-fat diet than
on a low-fat, high-carbohydrate diet.
Moreover, the low-fat,
high-carbohydrate diet caused an increase in triglyceride concentrations,
a risk factor for coronary heart disease, which was associated
with the liver fat production in both normal and high-insulin
individuals.
Researchers concluded
that the low-fat, high-carbohydrate diet might not be ideal, as
it can induce liver fat production and insulin resistance. This
is especially true when most of the carbohydrate is in the form
of simple sugars.
Reference
Source 89
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