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High Cholesterol at 40
Signals Heart Trouble Later
Excerpt
By Randy Dotinga, HealthDay
Researchers appear to have confirmed
what doctors have long suspected: High cholesterol levels among
people 40 and older translate into higher risks of heart disease
throughout their lives.
In other words, the cholesterol-rich
foods you eat today won't just spell trouble in the near future.
High cholesterol levels, on average, can as much as double your
lifetime risk of coronary disease, a new study found.
"We need to be much more aware
and much more active in identifying risk factors in young people
and intervening with them at an early stage, so their lifetime
risks are lower," says study co-author Dr. Donald M. Lloyd-Jones,
an assistant professor of medicine at Harvard Medical School.
High levels of cholesterol in the
blood contribute to coronary disease by creating blockages in
arteries and vessels. In the worst-case scenarios, the blockages
can cause heart attacks and other cardiovascular problems.
This new study marks the first
time researchers compared cholesterol levels at younger ages to
disease rates later in life, Lloyd-Jones says. "Most of the
focus has been on what cholesterol levels portend within the next
10 years or so."
Lloyd-Jones and colleagues examined
statistics from the Framingham Heart Study, an ongoing study that
began in 1948 and involves more than 10,000 people. "We can
look at lifetime experiences at certain cholesterol levels and
look at what the risk is for developing coronary disease,"
Lloyd-Jones says.
The findings appear in this week's
issue of Archives of Internal Medicine.
The researchers looked at people
who took part in the main study from 1971-1996. Their cholesterol
levels were measured at ages 40, 50, 60, 70 and 80.
The lifetime heart disease risks
for those with healthy cholesterol levels (under 200) at age 40
were 30 percent for men and 15 percent for women.
But when cholesterol levels at
age 40 rose to 200-239, the risk of coronary disease later in
life jumped to 43 percent for men and 26 percent for women. For
those with cholesterol levels of 240 or above, the levels skyrocketed,
to 57 percent and 33 percent for men and women, respectively.
The findings aren't surprising,
says Dr. Arthur Klatsky, a senior consultant in cardiology at
the Kaiser Permanente Medical Center in Oakland, Calif. But that
doesn't mean the study is unimportant, he adds.
"It indicates that the earlier
in life you begin to try to control this particular risk factor,
the more benefit you're likely to gain," Klatsky says. "It's
not a good idea to wait until you're in trouble. It's good for
everybody to check cholesterol, and if it's high, to do something
about it."
More information
Get an overview of coronary risk
factors from the American
Heart Association or the Texas
Heart Institute.
Reference
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