Hypertension
Traced to Infancy
Excerpt by Jennifer Thomas, HealthScoutNews
(HealthScoutNews) -- Can a tendency for
high blood pressure be traced to infancy?
A new study has found that babies who don't mind the taste of
salt have higher blood pressure than infants who can't stand the
stuff.
The researchers believe this early response to salt could indicate
which babies might go on to develop hypertension, or high blood
pressure. Here's the reasoning: a preference for salt in infancy
could indicate salt sensitivity, a condition in which salt in
the diet is a major factor in hypertension.
The link was made stronger because babies who had at least one
grandparent with hypertension had the highest blood pressure readings
of all, according to the study.
The researchers admit they're still a long way from being able
to detect in infancy who's going to get high blood pressure. But
ultimately, that's the goal, says Dr. Stephen Zinner, lead author
of the study and chairman of medicine at Harvard Medical School
in Boston.
"It's possible the tendency for hypertension might be predictable
early in life," Zinner says. "This study says a preference
in taste for salt in a newborn is related to higher blood pressure.
The implication is it might be a way of screening people who have
salt sensitivity and could be prone to higher blood pressures
or hypertension later in life."
The study appears in today's issue of Hypertension: Journal
of the American Heart Association.
Zinner and his colleagues gave 283 healthy, 3-day-old babies
a tiny taste of salt on a nipple. The researchers then measured
the babies' blood pressure and their "sucking response"
-- how vigorously they sucked on the salt.
None of the babies actually liked the taste of salt. Some just
minded it less than others, Zinner says.
Babies with a relative salt preference had blood pressures that
averaged 5 mmHg (millimeters of mercury) higher than babies who
had an "aversive" or "neutral" response.
The researchers measured the blood pressures again one month
later. Babies with a salt preference had a diastolic blood pressure
that averaged 3.1 mmHg higher and a systolic blood pressure that
averaged 3.3 mmHg higher than babies who liked salt the least.
Systolic is the first, or top, number on a blood pressure reading;
diastolic is the second, or lower, number.
The relationship between salt preference and blood pressure
was even stronger in newborns who also had a grandparent being
treated for high blood pressure. Babies in this group had a diastolic
blood pressure that was 5.0 mmHg higher and a systolic pressure
that was 6.7 mmHG higher than babies with an aversive response.
A month later, their pressures remained elevated.
None of the babies in the study had hypertension; some just
had higher readings than others.
The researchers also tested the babies' response to a sweet
taste and found no correlation between sucking response and blood
pressure.
Dr. Theresa Roca, a staff pediatric cardiologist at the Ochsner
Clinic in New Orleans, says that the study is interesting, but
that it's too early to use to help patients. It remains to be
seen if there is a link between a preference for salty foods in
adulthood and hypertension.
"It has never been shown that adults who are most salt-liking
are more prone to hypertension," Roca says. "You can't
base any management of patients on this research."
She also cautions that taking blood pressure readings from infants
is difficult, mainly because they squirm.
It's estimated that about 26 percent of Americans with normal
blood pressure and about 58 percent of those with hypertension
are salt sensitive, according to the National Heart, Lung, and
Blood Institute.
For adults who are salt sensitive, even a slight increase in
salt in their diet can cause an increase in blood pressure. African-Americans
are particularly susceptible to salt sensitivity, health experts
say.
Previous research has shown that a low-salt diet can decrease
blood pressure, both diastolic and systolic, by as much as 10
mmHg. A normal blood pressure reading for an adult is about 140
mmHg/90 mmHg, Roca says.
What To Do
The
American Dietetic Association has tips for reducing salt in
your diet. For more information on hypertension, visit the
National Hypertension Association.
Reference
Source 101
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