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Low Educational Level Tied
to Alzheimer's Disease
Excerpt
By Melissa
Schorr, Reuters Health
NEW YORK (Reuters Health)
- Elderly people with little formal schooling are more than twice
as likely as those with more education to be diagnosed with Alzheimer's
disease, according to new study findings.
``A low level of education is associated with an increased risk
of developing clinical Alzheimer's disease,'' noted lead author
Dr. Chengxuan Qiu of the Aging Research Center at the Karolinska
Institute in Stockholm, Sweden.
Previous research has suggested that a person's educational background
may be a risk factor for developing Alzheimer's disease, which
is the most common cause of dementia.
In their study, Qiu and colleagues followed 983 elderly patients
aged 75 years and older for an average of 2.8 years. During that
time, 147 patients were diagnosed with dementia, including 109
with Alzheimer's disease.
The study participants were classified by whether they had less
than 8 years of schooling (elementary school), 8 to 10 years of
education (high school level) or 11 years or more of schooling
(university level).
The report, published in the December issue of the Archives of
Neurology, indicates that patients with less than 8 years of schooling
or vocational training had more than twice the risk of being diagnosed
with Alzheimer's disease and a 70% greater chance of being diagnosed
with dementia.
While there was no difference in risk of dementia between those
who had obtained a high school or a college-level education, the
association between Alzheimer's and education was somewhat stronger
in women than in men.
The researchers note that one possible explanation for the association
is that those with higher educational levels may have a higher
standard of living, with a healthier lifestyle and less exposure
to toxins that could lead to neurological damage.
Another possible explanation is that those with more education
are better able to cope with or even ward off the pathological
changes in the brain associated with the disease.
However, while a lower educational level was associated with
a greater risk for death in general, it was not found to be a
risk factor for death among those with dementia or Alzheimer's
disease. In fact, those with a lower level of education who developed
Alzheimer's had a lower risk of mortality than those with a higher
level of education who developed the disease.
``Education may influence the clinical expression of Alzheimer's
disease or dementia, rather than affect the underlying pathological
process of the disease,'' Qiu concluded.
SOURCE: Archives of Neurology 2001;58:2034-2039.
Reference
Source 89
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