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Most Heart Attacks Caused
by Unhealthy Lifestyle
Excerpt
By Steven Sternberg, USA Today
Two sweeping studies released today
appear to explode the long-held myth that half of heart attacks
result from bad genes or bad luck.
The studies, focusing on different
populations totaling about half a million people, indicate that
about 90% of people with severe heart disease have one or more
of four classic risk factors: smoking, diabetes, high cholesterol
and high blood pressure.
That means the vast majority of
the 650,000 new heart attacks each year could be prevented or
delayed for decades by quitting smoking, reducing cholesterol
and controlling hypertension and diabetes.
"If we could eliminate smoking
and get people to be fit and trim, we could turn this thing around
without unraveling the genes that cause heart disease," says researcher
Eric Topol of the Cleveland Clinic Foundation. He is co-author
of a study involving more than 120,000 heart patients.
The research has major policy implications.
It suggests that doctors and patients should place even greater
emphasis on prevention. The American Heart Association and National
Cholesterol Education Program both have emphasized aggressively
treating people who have not yet had a heart attack if their "global
risk" is high.
"I think these studies will wake
people up and renew the emphasis on traditional risk factors,"
says Philip Greenland of Northwestern University. He is lead author
of a study involving almost 400,000 people enrolled in lifestyle
studies and followed for up to 30 years.
The researchers analyzed data from
previous major studies. The reports appear in today's Journal
of the American Medical Association.
"These papers are just amazing.
They're basically blowing away the myth that only half of the
people who have heart disease have traditional risk factors,"
says John Canto of the University of Alabama-Birmingham. He co-wrote
an accompanying editorial in the journal.
None of the researchers could identify
the source of the erroneous assertion, cited by experts for years.
"It's folklore," Greenland says.
A separate analysis in the journal
concludes that there isn't enough evidence to conclude that so-called
new risk factors for heart disease, including inflammatory proteins
called Lipoprotein-A, C-reactive protein and homocysteine, add
much to the predictive value of the four classic risks.
Reference
Source 106
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