Scientists
Use Nose Cells
to Try to Repair Spine
Excerpt
By Marilyn Bitomsky, Reuter's Health
BRISBANE (Reuters Health) - A team of scientists in Australia
is attempting to repair spinal cord injuries for the first time
using cells collected from a patient's nasal passage.
The first historic 8-hour operation was conducted in June and, although
team members were guarded in their responses, it appears that more
than one operation may be performed.
This first trial will consist of eight patients, some of whom
are yet to be recruited.
The researchers transplanted a type of cell found inside the
nose, known as olfactory ensheathing cells, into the spinal cord
of a volunteer paraplegic patient.
By collecting the cells from the patient's nose, problems of
rejection were eliminated.
Although the trial team was careful not to raise false hopes
that the procedure will be a cure for paralysis, there is a chance
that the cells "will do something positive for these people,"
said ear nose and throat specialist, Dr. Chris Perry, of Princess
Alexandra Hospital in Brisbane.
He expects the patient to possibly regain some feeling and have
some improvement in bladder and bowel function.
In addition to Perry, the research team includes Princess Alexandra
Hospital spinal injuries unit head Dr. Tim Geraghty, and Griffith
University scientists Professor Alan Mackay-Sim and Dr. Francois
Feron. They began planning the trial 2 years ago.
The actual procedure began when Perry harvested nasal tissue
from the patient several weeks before the operation at Princess
Alexandra Hospital.
Olfactory ensheathing cells are a type of cell more typically
found in the brain and spinal cord and their easy accessibility
avoids the need for removing cells from the brain itself. Unlike
other nerve cells in the body, these cells are unique that they
are continually regenerated throughout life.
The cells were then grown in the laboratory by the Griffith
University scientists, representing the first time such cells
had been harvested from the nose and grown in such a manner.
The Griffith scientists and colleagues from the University of
New South Wales had already demonstrated that the cells could
spur regeneration in the injured spinal cords of laboratory rats.
Fourteen million cells were dissolved in two drops of fluid
and transplanted into several areas of the patient's injured spinal
cord.
The cells were injected with a specially assembled surgical
device developed by the team and made at Griffith University.
This allowed the cells to be injected through extremely fine
needles, they said.
Reference
Source 89
For more information on how to prevent other diseases, use
PreventDisease.com's "Quick
Prevention Resources".
|