Obesity
Ups Cataract Risk: Study
Excerpt
By Suzanne Rostler, Reuter's Health
NEW YORK (Reuters Health) - On top
of all the other problems related to being very overweight, researchers
now report that obesity can increase the risk of developing cataracts,
the world's leading cause of blindness.
Cataracts occur when proteins in
the eye's lens begin to clump together, forming a milky cloud
that obscures vision. Everyone will experience some clouding in
the eye lens if they live long enough.
But according to new findings,
the risk rises in tandem with body mass index (BMI), a measure
of weight in relation to height. A BMI below 25 is considered
healthy while obesity is marked by a BMI of at least 30. Those
who fall in the middle are considered to be overweight or at risk
for a host of chronic disorders.
In the study, middle-aged men and
women with a BMI of at least 30 were 36% more likely than their
leaner peers to develop cataracts. There was no relationship between
obesity and nuclear cataracts, the most common type of cataract
that strikes the center of the eye. The risk of developing a posterior
subcapsular cataract, the most visually disabling type that forms
in the back of the lens, rose by 68% among obese adults, the investigators
found.
It is not clear from the current
report how obesity may contribute to cataracts, but the researchers
suggest that poor blood sugar control or elevated levels of inflammatory
compounds in the body, both of which can occur in obese individuals,
may play a role.
While more research is needed,
the report published in the International Journal of Obesity indicates
that maintaining a healthy body weight may prevent or delay the
onset of cataracts and reduce the need for cataract surgery, which
involves removing the cloudy lens and replacing it with an implant.
Although cataract surgery can restore
vision, it is costly and not available in less developed countries,
according to Dr. June M. Weintraub, currently with the San Francisco
Department of Public Health in California, and her colleagues
from the Harvard School of Public Health in Boston, Massachusetts.
"Obesity is related to numerous
chronic diseases, and the causal relationship between obesity
and cataract extraction...adds further indication of the burden
of obesity on our society," Weintraub explained in an interview
with Reuters Health.
She suggested that understanding
that obesity can increase the risk of developing cataracts might
motivate some individuals to control their weight.
The study involved more than 130,000
US adults aged 45 years and older who did not have a cataract
when the study began. Over the next 10 to 16 years, researchers
tracked the development of cataracts and their relationship to
BMI.
SOURCE: International Journal of
Obesity 2002;10.1038/sj.ijo.802158.
Reference
Source 89
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