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Smoking
as Harmful as Drugs to Fetus
Excerpt
By
K.L. Capozza,
HealthScoutNews
In a discovery that could change
the way health officials view smoking during pregnancy, Brown
University researchers show nicotine has the same impact on fetuses
as cocaine and heroin.
Babies exposed to nicotine during
pregnancy were more excitable and tense, the researchers say,
and they showed signs of central nervous system and gastrointestinal
stress.
The report, published in the June
issue of Pediatrics, suggests the infants experienced "neonatal
withdrawal" from nicotine, although the finding was not conclusive.
"Because we evaluated the
babies at one to two days following birth, we don't know if it's
actually withdrawal we're seeing or the effects of [the mother's]
cigarette smoking," says study author Karen L. Law, a third-year
medical student at Brown.
What's clear is that nicotine may
have the same toxic effect as illegal drugs, Law adds. Ideally,
the finding might motivate the 18 percent of pregnant women who
smoke to quit.
The study compared the behaviors
of 27 nicotine-exposed newborns and 29 unexposed newborns 48 hours
after birth. The researchers measured the nicotine intake of mothers
by asking them how many cigarettes they smoked per day and then
verifying their answers by measuring a biological marker of nicotine
called cotinine, which is found in saliva.
They found that a mother's cigarette
intake correlated with an increase in symptom severity in her
newborn.
"The present study is the
first to establish that the predictions from animal models are
indeed true -- behavioral abnormalities akin to those associated
with illicit drugs used during pregnancy, are equally, or perhaps
even more, detectable in the offspring of women who smoke during
pregnancy," says Theodore Slotkin, a professor of pharmacology
and cancer biology at Duke University Medical Center.
"This is an important, even
essential, contribution to the field, especially as many of the
women in the study were smoking fairly low numbers of cigarettes,"
he adds.
The results also suggest there
may be legal grounds for removing children from mothers who smoke
during pregnancy, say the researchers.
Given that nicotine is showing
the same effects as an illegal substance for which protective
services will remove babies from their mothers, policy makers
ought to reconsider how they evaluate a fit mother, writes senior
study author Barry Lester, a professor of psychiatry and human
behavior at Brown.
"To have these results in
which these nicotine-exposed babies have a similar profile as
cocaine-addicted infants makes us take a step back and ask what's
appropriate behavior during pregnancy. Somehow smoking is still
acceptable," Law says. "We need to take a look at why
one substance over another is not controlled during pregnancy."
The study did not look at the long-term
impact of nicotine exposure during pregnancy, but the researchers
say previous studies suggest the impact of smoking on newborns
can be mediated if the family provides appropriate attention and
care throughout childhood.
More information
For more on the dangers of smoking,
see the U.S. Centers
for Disease Control and Prevention, and here are the reasons
why expectant
moms should quit smoking.
Reference
Source 101
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