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Study
Links Vaccine
Ingredient to Autism in Mice
A study of specially bred mice suggests that a mercury preservative
in vaccines could potentially cause some of the brain changes
in autism, U.S. researchers said.
The publication of the study gives
fuel to an alliance of environmentalists, parents of children
with autism, anti-vaccine advocates and politicians who say they
will continue to fight to prove that vaccines can cause autism
in susceptible children.
But experts who issued a report
last month saying there was no link between vaccines and autism
said they had already seen the study and rejected it.
Dr. Mady Hornig of Columbia University
in New York said her study shows the possibility that a genetic
predisposition could leave certain children vulnerable to a range
of toxins in vaccines, including a mercury-based preservative
called thimerosal.
Writing in the journal Molecular
Psychiatry, Hornig said specially bred mice that have deficient
immune systems did show changes in behavior after getting the
equivalent of the childhood vaccinations given to U.S. babies
and toddlers.
"I think that these findings suggest
that it is very plausible that there could be a genetic factor
that creates risk for some individuals with autism," Hornig said
in a telephone interview.
INSTITUTE OF MEDICINE REPORT
Hornig presented her findings in
February to an Institute of Medicine committee examining the potential
link between vaccines and autism.
The institute is an independent
body that advises the federal government on health matters.
The committee issued a report last
month saying there was no evidence that vaccines or thimerosal
could cause autism and advised that research funds looking for
the cause of autism would be better spent elsewhere.
Hornig said her research could
at the very least be used to reassure parents worried about the
safety of vaccines.
Her study was done using a combination
of private and federal funds, including money from SafeMinds,
a group pursuing the link between all types of mercury and brain
disease.
But Dr. Marie McCormick of Harvard
University's School of Public Health, who chaired the panel, said
Hornig's research stretched credibility. For instance, it is not
clear that children with autism have impaired immune systems.
And using specially bred mice takes
research a long way away from real-life situations in people.
"Even though she says these behaviors
are like autism, it is not clear that these behaviors are analogous
to autism," McCormick said.
- Asthma
& Vaccines
Reference
Source 89
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