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Sushi May Protect Against
Rare Type of Lung Cancer

LONDON (Reuters Health) - The Japanese love of fresh fish--particularly sushi--may protect them against lung cancer, according to a report in this week's British Journal of Cancer.

Dietary factors such as frequent consumption of soybean products, green tea and fish have long been thought to be one reason why Japanese lung cancer deaths and incidence rates are less than two-thirds those in the United States and the UK. However, study findings have often been inconclusive or contradictory.

To investigate the issue further, scientists from the Cancer Center Research Institute and Cancer Center Hospital of Aichi, Japan, looked at the diets of over 1,000 Japanese men and women with different types of lung cancer and compared them with over 4,000 healthy individuals.

The study found that people who ate the most fresh fish were only half as likely to develop rare cancers of the lung called adenocarcinoma compared with people who ate the least fresh fish. Dried and salted fish consumption was not associated with any protective effect against lung cancer.

Fresh fish rich in fish oil containing polyunsaturated fatty acids may be the reason for the protective effect, the researchers noted. ``The relatively lower mortality rate of lung cancer in Japan might thus be at least partly attributable to higher consumption of fish,'' they report.

Even though the protective effect was only significant in the case of adenocarcinomas, a particularly rare type of lung cancer, lead study author Professor Toshiro Takezaki said in a news release, ``Japanese people love their fresh fish, particularly sushi. We think that is why, even though the Japanese smoke as much as people in the UK, their rate of lung cancer is only two-thirds as high.''

Professor Gordon McVie, director general of The Cancer Research Campaign, which publishes the British Journal of Cancer, added, ``This research once again emphasises the important interaction of diet with tobacco in deciding whether we will develop lung cancer. The most important thing anyone can do to cut their risk from lung cancer is to give up smoking, but for those people who are unable to quit, eating lots of fresh fish could be a useful way to moderate their risk.''

SOURCE: British Journal of Cancer 2001;84.

Reference Source 89

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