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Tomato
Supplements
May Not Affect Cancer
Excerpt
by Maggie Fox,
Reuters Health
Supplements based on tomato extracts
may not work to prevent prostate cancer the way the whole fruit
does, at least in rats, researchers reported.
The research, published in the
Journal of the National Cancer Institute, suggests that men seeking
to benefit from the health-giving properties of tomatoes will
have to eat tomato sauce, paste or the whole fruit instead of
popping a pill.
"Our findings strongly suggest
that risks of poor dietary habits cannot be reversed simply by
taking a pill," Dr. Steven Clinton of Ohio State University, who
helped lead the study, said in a statement.
"We shouldn't expect easy solutions
to complex problems. We must focus more on choosing a variety
of healthy foods, exercising and watching our weight."
Many studies have found that men
who eat tomato products have a lower risk of prostate cancer,
and scientists have credited the lycopene -- the compound that
makes tomatoes red. But other experts say whole foods contain
a variety of compounds that work together for healthful benefits.
Lycopene is an anti-oxidant, which
means it can help deflect chemicals that damage cells, leading
to the changes that underlie cancer.
Teams at the University of Illinois
in Urbana-Champaign and Ohio State University in Columbus did
carefully controlled studies on rats to see if lycopene supplements
-- already on the market -- could provide the same benefits as
cooked or raw tomatoes.
They treated 194 male rats with
a chemical that induces prostate cancer and then gave some rats
whole tomato powder, some pure lycopene and the rest a standard
diet with no supplements. After four weeks, the rats were further
divided into two groups: a group with unlimited access to food
and a group given 80 percent of what the others ate.
Rats fed the tomato powder diet
were 26 percent less likely to die of prostate cancer than rats
not given any supplements. The rats given lycopene were only slightly
more likely to survive than rats given no tomato products.
"Many men are consuming lycopene-containing
supplements with the hope that they may prevent prostate cancer
or enhance the treatment of their prostate cancer," the researchers
wrote.
"Our study does not say that lycopene
is useless," Clinton added. "Instead it suggests that if we want
the health benefits of tomatoes, we should eat tomatoes or tomato
products and not rely on lycopene supplements alone."
In another piece of bad news for
men who would like to keep eating the typical American diet rich
in fat and calories, the researchers found that rats fed the fewest
calories per day had a lower risk of prostate cancer.
Rats in the diet-restricted group
had a 32 percent lower risk of dying with prostate cancer than
rats with unlimited access to food, no matter which supplement
they got.
Dr. John Erdman, a professor of
food science, human nutrition and internal medicine at the University
of Illinois, added, "We believe people should consume whole tomato
products -- in pastas, in salads, in tomato juice and even on
pizza."
Either way, the tomato products
did not work miracles. After 14 months -- a lifetime for a rat
-- 62 percent of the rats fed tomato powder had died of prostate
cancer.
Reference
Source 89
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